| Entry |
|
|---|
| Name |
Tenoxicam (JAN/USAN/INN);
Tilcotil (TN) |
|---|
| Formula |
C13H11N3O4S2
|
|---|
| Exact mass |
337.0191
|
|---|
| Mol weight |
337.3741
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01910 Anti-inflammatory drug, oxicams
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-inflammatory, COX inhibitor |
|---|
| Comment |
Oxicams
Nonsteroidal anti-inflammatory drug (NSAID)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AC Oxicams
M01AC02 Tenoxicam
D01767 Tenoxicam (JAN/USAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01910 Anti-inflammatory drug, oxicams
D01767 Tenoxicam
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
D01767 Tenoxicam
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D01767 Tenoxicam (JAN/USAN/INN)
PTGS2 (COX2)
D01767 Tenoxicam (JAN/USAN/INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D01767
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| Other DBs |
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| KCF data |
ATOM 22
1 S2x S 22.9655 -19.9925
2 N4y N 24.1749 -19.2919
3 C8y C 24.1749 -17.8906
4 C8y C 22.9655 -17.1899
5 C5a C 25.3797 -17.1899
6 N1b N 26.5899 -17.8906
7 C8y C 27.8001 -17.1899
8 O5a O 25.3783 -15.7886
9 N5x N 29.0120 -17.8877
10 C8x C 30.2222 -17.1870
11 C8x C 30.2205 -15.7886
12 C8x C 29.0086 -15.0909
13 C8x C 27.7984 -15.7915
14 O3c O 21.7421 -20.6861
15 O3c O 24.1695 -20.6932
16 C8y C 21.7490 -19.2919
17 C8y C 21.7458 -17.8901
18 S2x S 20.4116 -17.4600
19 C8x C 19.5905 -18.5960
20 C8x C 20.4170 -19.7282
21 O1a O 22.9682 -15.7886
22 C1a C 25.3890 -19.9917
BOND 24
1 16 1 1
2 7 9 2
3 9 10 1
4 10 11 2
5 11 12 1
6 12 13 2
7 13 7 1
8 5 6 1
9 1 14 2
10 1 2 1
11 1 15 2
12 6 7 1
13 2 3 1
14 5 8 2
15 3 4 2
16 4 17 1
17 16 17 2
18 17 18 1
19 18 19 1
20 19 20 2
21 20 16 1
22 4 21 1
23 3 5 1
24 2 22 1
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